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From Chapter 1:
Another tradition gives the old Pied Bull at Islington, long since demolished, as the scene of the momentous event. It is said in its earlier days to have been a country house of Sir Walter's, and according to legend it was in his dining-room in this house that he had his first pipe. Hone, in the first volume of the "Every Day Book" tells how he and some friends visited this Pied Bull, then in a very decayed condition, and smoked their pipes in the dining-room in memory of Sir Walter. From the recently published biography of William Hone by Mr. F.W. Hackwood, we learn that the jovial party consisted of William Hone, George Cruikshank, Joseph Goodyear, and David Sage, who jointly signed a humorous memorandum of their proceedings on the occasion, from which it appears that "each of us smoked a pipe, that is to say, each of us one or more pipes, or less than one pipe, and the undersigned George Cruikshank having smoked pipes innumerable or more or less," and that "several pots of porter, in aid of the said smoking," were consumed, followed by bowls of negus made from "port wine @ 3s. 6d. per bottle (duty knocked off lately)" and other ingredients. Speeches were made and toasts proposed, and altogether the four, who desired to "have the gratification of saying hereafter that we had smoked a pipe in the same room that the man who first introduced tobacco smoked in himself," seem to have thoroughly enjoyed themselves.

From Chapter 5:
Among the many medicinal virtues attributed to tobacco was its supposed value as a preservative from contagion at times of plague. Hearne, the antiquary, writing early in 1721, said that he had been told that in the Great Plague of London of 1665 none of those who kept tobacconists' shops suffered from it, and this belief no doubt enhanced the medical reputation of the weed. I have also seen it stated that during the cholera epidemics of 1831, 1849, and 1866 not one London tobacconist died from that disease; but good authority for the statement seems to be lacking. Hutton, in his "History of Derby," says that when that town was visited by the plague in 1665, that at the "Headless-cross ... the market-people, having their mouths primed with tobacco as a preservative, brought their provisions.... It was observed, that this cruel affliction never attempted the premises of a tobacconist, a tanner or a shoemaker." Whatever ground there may have been for the belief in the prophylactic effect of smoking, there can be no doubt that in the seventeenth century it was firmly held. Howell in one of his "Familiar Letters" dated January 1, 1646, says that the smoke of tobacco is "one of the wholesomest sents that is against all contagious airs, for it overmasters all other smells, as King James they say found true, when being once a hunting, a showr of rain drave him into a Pigsty for shelter, wher he caus'd a pipe full to Be taken of purpose." But here Mr. Howell is certainly drawing the long-bow. One cannot imagine the author of the "Counterblaste" countenancing the use of tobacco under any circumstances.